Aberrant DNA methylation of the toll-like receptors 2 and 6 genes in patients with obstructive sleep apnea.
Obstructive sleep apnea (OSA) is a syndrome leading to chronic intermittent hypoxia, and the up-regulation Pastry Forks of toll-like receptors (TLR) 2 and 6 on peripheral blood cells has been reported.We hypothesized that DNA methylation in TLR2 and TLR6 genes may play a role in the development of OSA and its excessive daytime sleepiness (EDS) phen